Fantastic Voyage is a 1966 American submarine science fiction adventure film directed by Richard Fleischer and written by Harry Kleiner, based on a story by Otto Klement and Jerome Bixby. The film is about a submarine crew who are shrunk to microscopic size and venture into the body of an injured scientist to repair damage to his brain.
The United States and the Soviet Union have both developed technology that can miniaturise matter by shrinking individual atoms, but only for one hour. (The novel stated that the duration of miniaturiasation is inversely proportional to its degree. A 50% reduction, say, could be maintained for many days, but a reduction to microbial size could last for only an hour.)
Scientist Dr. Jan Benes (Jean Del Val), working behind the Iron Curtain, has figured out how to make the process work indefinitely. With the help of American intelligence agents, including agent Charles Grant (Boyd), he escapes to the West, but an attempted assassination leaves him comatose with a blood clot in his brain that no surgery can remove from the outside.
Bantam Books obtained the rights for a paperback novelisation based on the screenplay and approached Isaac Asimov to write it. Because the novelisation was released six months before the movie, many people mistakenly believed that the film was based on Asimov’s book.
The film won two Academy Awards and was nominated for three more.